⇨  Teams


Our research is focused on the understanding of cellular mechanisms underlying the regulation of emotions, from social interaction to pain and anxiety.

Therefore, we do explore how central neuropeptides modulate the neuroglia network in emotion-related structures, such as amygdala. For this purpose we combine ex vivo and in vivo approaches of electrophysiology and calcium imaging to genetic tools.

Team projects

Alexandre Charlet


Pascal Darbon


Pierre-Alexis Derrien

Postdoctoral fellow / Ph.D. students
Valentin Grelot

Emotions sush as : love, anger, pain and fear are necessary for individual’s life, and even for survival. To better understand these complex processes, we are studying the effect of an important neuropeptide in emotional modulation : oxytocin. More precisely, we are attempting to demonstrate its effects on astrocytes, a cell type known to play an important role in modulating the neural network, in order to better explain emotional behavior in mammals.


Kai-Yi Wang

  • Prof. Hibert group understanding the architecture of G-protein coupled receptors, University of Strasbourg, France
  • Prof. Grinevich group central mechanisms of stress responses, Mannheim University, Germany
  • Prof. Javier Stern group CNS mechanisms in cardiometabolic diseases, Georgia State University, USA
  • Prof. Bice Chini group Neurobiology of oxytocin and vasopressin receptors, CNR Neuroscience Institute, Milan, Italy.
  • Dr. Nathalie Rouach group neuroglial interactions in cerebral physiopathology, Collège de France, Paris, France.
  • Prof. Marc Landry, Bordeaux, France; Prof Andrew Gundlach, Melbourne, Australia.
  • Prof. Andrew Gundlach group peptide neurobiology, Florey Institute of Neuroscience and Mental Health, Australia.
  • Prof. Landry group purinergic-mediated neuroinflammation and brain disorders, UMR5293, Bordeaux, France.
  • Dr. Yalcin group neuroanatomy, pain and psychopathology, UPR3212, Strasbourg, France.
  • Prof Marcel Hibert, Strasbourg, France; Benephyt startup.
  • Dr. Simonin group GPCRs, pain and inflammation, UMR7242, Strasbourg, France.
  • Dr. Bihel group chemogenomic and medicinal chemistry, UMR7200, Strasbourg, France.
  • Benephyt startup, France.

Our Publications